Due to the Pygmy Marmosets size they are not as vulnerable as their larger cousins, they are highly adaptable and can live in many high up places in the rainforest. Pygmy Marmosets can hide in true foliage when predators come near, although they cannot hide from habitat destruction. This is the biggest threat to Pygmy Marmosets, humans cutting down trees for farming, paper mills, and mining threaten these animals. If we do not conserver our rainforest Pygmy Marmosets are likely to disappear off the face of the earth.

Big natural predators to Pygmy Marmosets are Boa Constrictors, usually 10-14 feet they live in the tropical parts of South America. They will hang from trees and catch prey, they have excellent camouflage. The Boa Constrictor can swallow a tiny Pygmy Marmoset whole.
Pythons are another threat to our Pygmy Marmoset friends. They are one of the largest snake species in the world. The Python will wrap around its enemy, suffocating it to death.
Another Predator to Pygmy Marmosets I the harpy eagle, which is the largest and most powerful bird of prey on earth. This carnivore lives in South America and will swoop down killing Pygmy Marmosets.